What is this medication for?
Ondansetron belongs to the class of medications called 5-HT3 receptor
antagonists. This medication is used for the prevention of nausea
and vomiting associated with certain types of cancer
chemotherapy and radiation. It is also used to prevent and treat the nausea
and vomiting that occurs after surgery. It works by reducing the effects
of a naturally-occurring chemical in the body called serotonin which causes
nausea and vomiting.
Your doctor may have suggested this medication for conditions other than those
listed here. As well, some forms of this medication may not be used for all
of the conditions discussed here. If you have not discussed this with your doctor
or are not sure why you are taking this medication, speak to your doctor. Do
not give this medication to anyone else, even if they have the same symptoms
as you do. It can be harmful for people to take this medication if their
doctor has not prescribed it. Do not stop taking this medication without
consulting your doctor.
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
How should I use this medication?
Ondansetron is given as an injection in the hospital under close supervision
by health care providers. Normally, the doctor would prescribe ondansetron tablets
or solution (e.g., discharge from the hospital or follow-up visits with the
doctor) for regular daily use.
The recommended adult dose is based on need and ranges from 8 mg to
32 mg daily given in divided doses.
Prevention of nausea and vomiting related to chemotherapy or radiation for
adults and children over 12 years old: Give one 8 mg dose 30
minutes prior to chemotherapy treatment, followed by 8 mg every
8 to 12 hours for up to two days. Children from 4 to 11 years of age may be
given 4 mg 30 minutes before chemotherapy treatment, followed by
4 mg given three times daily.
Prevention of nausea and vomiting related to surgery for adults: Give
one 16 mg dose one hour before receiving anesthetics.
Orally disintegrated tablet should be taken by placing it on top of the tongue
where it dissolves in seconds, then swallow with saliva.
Store this medication at room temperature, protect it from light, and keep
it out of the reach of children.
Many things can affect the dose of medication that a person needs, such as
body weight, other medical conditions, and other medications. If your doctor
has recommended a dose different from the ones listed here, do not change
the way that you are taking the medication without consulting your doctor.
It is very important that this medication be taken exactly as prescribed by
your doctor. If you miss a scheduled dose of this medication take it as soon
as you remember it. If it is almost time for your next dose, skip the missed
dose and carry on with your regular schedule. Do not take a double dose to
make up for a missed one.
Who should NOT take this medication?
Ondansetron should not be used by anyone who is allergic to ondansetron or any ingredients of this medication.